OAS2 Rabbit pAb
Product Details
- Cat. No.
- A17428
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - OAS2 antibody (A17428)
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Description
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
