Product & ReviewsAntibodies
ORAI2 Antibody
Product Details
- Cat. No.
- 253717
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human ORAI2.
- Isotype: Rabbit Ig
- Gene: Q96SN7
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Western Blotting (WB)