Product & ReviewsAntibodies
p27Kip1 Antibody
Product Details
- Cat. No.
- 251783
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Cyclin-dependent kinase inhibitor p27 (p27Kip1) is regulator of cell cycle progression. p27Kip1 is involved in G1 arrest, and is a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. P27Kip1 forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Defects in CDKN1B are the cause of multiple endocrine neoplasia type 4 (MEN4). Multiple endocrine neoplasia (MEN) syndromes are inherited cancer syndromes of the thyroid.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: Recombinant rodent p27Kip1 protein.
- Clone: IMD-27
- Isotype: Mouse IgG1
- Gene: P46527
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Western Blotting (WB)