Product & ReviewsAntibodies
P2RX7 Rabbit pAb
Product Details
- Cat. No.
- A10511
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - P2RX7 antibody (A10511)
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Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
