Product & ReviewsAntibodies
p38 MAPK Antibody
Product Details
- Cat. No.
- 251128
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. P38 MAPK plays a critical role in the production of some cytokines, for example IL-6. P38 MAPK plays a role in stabilization of EPO mRNA during hypoxic stress.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chimpanzee, Guinea Pig, Hamster, Human, Mammalian, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p38 MAPK.
- Isotype: Rabbit Ig
- Gene: Q16539
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunoprecipitation (IP)
- Western Blotting (WB)