Product & ReviewsAntibodies

p38 MAPK (Thr180/Tyr182) Antibody

Product Details

Cat. No.
252567
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. P38 MAPK plays a critical role in the production of some cytokines, for example IL-6. P38 MAPK plays a role in stabilization of EPO mRNA during hypoxic stress. p38 MAPK is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Chicken, Dog (Canine), Human, Monkey, Mouse, Rat, Zebrafish
  • Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr180/Tyr182 of rat p38 MAPK.
  • Isotype: Rabbit Ig
  • Modifications: Phosphospecific Antibody
  • Gene: P70618

Handling

  • Quantity: 0.1 ml
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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