Product & ReviewsAntibodies
PAK-4 Antibody
Product Details
- Cat. No.
- 251925
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Serine/threonine-protein kinase PAK 4 (PAK4) activates the JNK pathway. PAK4 plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. PAK4 phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Rabbit (Lapine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PAK4.
- Isotype: Rabbit Ig
- Gene: O96013
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)