PAK2 (3B5) Antibody
Product Details
- Cat. No.
- 252896
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
PAK2 (P21-activated kinase 2) is a serine/threonine kinase. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Monkey
- Antigen: Purified recombinant fragment of PAK2 expressed in E. coli.
- Clone: 3B5
- Isotype: Mouse IgG1
- Gene: P38936
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)