Product & ReviewsAntibodies

PAPP-A (1_24) Antibody

Product Details

Cat. No.
250220
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21). This antibody is specific for native human PAPP-A. Heat and SDS-denatured PAPP-A is also recognized, but not acid treated PAPP-A .

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: Purified human PAPP-A
  • Clone: 1_24
  • Isotype: Mouse IgG1/k
  • Gene: Q13219

Handling

  • Quantity: 0.2 mg
  • Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.

Applications

  • ELISA (ELISA)
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