Product & ReviewsAntibodies
PAPP-A (1_24) Antibody
Product Details
- Cat. No.
- 250220
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21). This antibody is specific for native human PAPP-A. Heat and SDS-denatured PAPP-A is also recognized, but not acid treated PAPP-A .
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified human PAPP-A
- Clone: 1_24
- Isotype: Mouse IgG1/k
- Gene: Q13219
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)