Product & ReviewsAntibodies
PAR-4 Antibody
Product Details
- Cat. No.
- 251943
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Prostate apoptosis response 4 protein (PAR4) is a pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. PAR-4 induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NFkB transcriptional activity. PAR-4 is widely expressed but is found elevated in various neurodegenerative diseases.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PAR-4.
- Isotype: Rabbit Ig
- Gene: Q96IZ0
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)