Product & ReviewsAntibodies
Parkin (Ser378) Antibody
Product Details
- Cat. No.
- 252571
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Parkin is an E3 ligase in the ubiquitin-proteasome system. Hereditary Parkinson’s disease is most commonly caused by mutations in the parkin gene and is characterized by the progressive loss of dopaminergic neurons and the presence of Lewy bodies in the substania nigra. Recent evidence suggests that phosphorylation of parkin at Ser378 may have an important regulatory role on its E3 ubiquitin ligase activity.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser378 of human parkin.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: O60260
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)