Product & ReviewsAntibodies
PARP-14 Antibody
Product Details
- Cat. No.
- 251941
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Poly [ADP-ribose] polymerase 14 (PARP-14) functions as a transcriptional switch for Stat6-dependent gene induction. In the absence of a signal, PARP-14 acts as a transcriptional repressor by recruiting histone deacetylases (HDACs). In contrast, in the presence of IL-4 the catalytic activity of PARP-14 facilitates Stat6 binding to the promoter, and release of HDACs so as to activate transcription.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PARP-14.
- Isotype: Rabbit Ig
- Gene: Q460N5
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)