Product & ReviewsAntibodies
Pax-6 Antibody
Product Details
- Cat. No.
- 251935
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Paired box protein (Pax-6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Pax-6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Pax-6 regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Defects in Pax-6 are associated with a number of diseases and abnormalities of the eye and optic nerve.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Pax-6.
- Isotype: Rabbit Ig
- Gene: P26367
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)