Product & ReviewsAntibodies
PAX6 (1C8) Antibody
Product Details
- Cat. No.
- 253026
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Pax-6 (Paired box protein) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Pax-6 is required for the differentiation of pancreatic islet alpha cells, competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Pax-6 regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Defects in Pax-6 are associated with a number of diseases and abnormalities of the eye and optic nerve.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of human PAX6 expressed in E. coli. <br>"
- Clone: 1C8
- Isotype: Mouse IgG1
- Gene: P26367
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)