Product & ReviewsAntibodies
PCNA Rabbit mAb
Product Details
- Cat. No.
- A12427
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - PCNA Rabbit mAb (A12427)
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Description
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
