Product & ReviewsAntibodies
PDGFRA Antibody
Product Details
- Cat. No.
- 250816
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The PDGF receptor type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen) a 170kD protein, binds all three isoforms of PDGF with high affinity; whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity . Both receptors are trans membranous, ligand activated protein tyrosine kinases which phosphorylate a number of important signal transduction proteins that are bound with differential affinities via SH2 domains.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PDGF-R-A.
- Isotype: Rabbit Ig
- Gene: P16234
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)