Product & ReviewsAntibodies

PDGFRB Antibody

Product Details

Cat. No.
250817
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

The PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity, whereas the PDGF receptor type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity. Both receptors are trans membranous, ligand activated protein tyrosine kinases which phosphorylate a number of important signal transduction proteins that are bound with differential affinities via SH2 domains.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PDGF-R-B.
  • Isotype: Rabbit Ig
  • Gene: P09619

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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