Product & ReviewsAntibodies
PEG10 Antibody
Product Details
- Cat. No.
- 251455
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
PEG10 (Paternally expressed gene 10 protein) participates apoptosis and cell differentiation pathways. PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 also plays a role in cell growth promotion and hepatoma formation. PEG10 inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, PEG10 induces the formation of cellular extension, such as filopodia in association with ALK1.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PEG10.
- Isotype: Rabbit Ig
- Gene: Q86TG7
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)