Peptide YY Antibody
Product Details
- Cat. No.
- 250241
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
PYY (peptide tyrosine-tyrosine amide) is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1. This antibody binds human PYY. Cross-reactivity with NPY or PP in solution was <0.1%.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Synthetic human PYY coupled to carrier with glutaraldehyde adsorbed onto aluminum hydroxide gel and emulsified in Freund's incomplete adjuvant.
- Clone: NA
- Isotype: Mouse IgG1/k
- Gene: P10082
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)