Product & ReviewsAntibodies

Phospho-BRAF-S445 Rabbit pAb

Product Details

Cat. No.
AP0012
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
ABclonal Technology

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Rat

Handling

    Applications

      Specificity rating
      Sensitivity rating
      Quality rating
      Write your own review

      Product Overview

      Links