Product & ReviewsAntibodies

Phospho-NAK/TBK1-S172 Rabbit mAb

Product Details

Cat. No.
AP1026
Type
Primary Antibody
Clonality
Monoclonal
Host
Rabbit
ABclonal Technology

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Description

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

Biological Information

  • Clonality: Monoclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse

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