Phospho-VEGF Receptor 2-Y996 Rabbit pAb
Product Details
- Cat. No.
- AP0595
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human