PIK3C3 Rabbit pAb
Product Details
- Cat. No.
- A0952
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse