PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-kB kinase/NF-kB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas.
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human
- Clone: CHU61
- Isotype: IgG2a
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -80C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Immunohistochemistry (IHC)
- Western Blotting (WB)
