Product & ReviewsAntibodies

PIM2 rat antibody (mAb) (Clone CHU61), sample

Product Details

Cat. No.
61160
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Active Motif

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Description

PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-kB kinase/NF-kB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Human
  • Clone: CHU61
  • Isotype: IgG2a

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -80C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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