Product & ReviewsAntibodies

PKM2 rabbit antibody (pAb)

Product Details

Cat. No.
61423
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

PKM2 (pyruvate kinase M2 isoform) is a glycolytic enzyme that catalyses the conversion of phosphoenolpyruvate to pyruvate. In mammals, the M1 isoform (PKM1) is expressed in most adult tissues. The M2 isoform (PKM2), an alternatively-spliced variant of M1, is expressed during embryonic development, is upregulated in human cancer cells and has been implicated in transcriptional regulation. Recently PKM2 has been described to bind to Histone H3 and phosphorylate threonine 11 (H3T11ph) which implicates PKM2 as an epigenetic regulator of gene expression.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Isotype: IgG

Handling

  • Quantity: 100 ul
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Western Blotting (WB)
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