Product & ReviewsAntibodies
PLK-1 (Thr210) Antibody
Product Details
- Cat. No.
- 252572
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles.Deregulated expression of PLK’s is detected in many types of cancer and associated with oncogenesis. It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Monkey, Mouse, Rat, Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr210 of rat polo-like kinase.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: P53350
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)