Product & ReviewsAntibodies
PMP-22 Antibody
Product Details
- Cat. No.
- 250827
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Peripheral myelin protein 22 (PMP-22) is an integral membrane protein involved in growth regulation and myelinization in the peripheral nervous system. PMP-22 is found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Defects in PMP22 are the cause of hereditary motor and sensory neuropathies, including Charcot-Marie-Tooth disease type 1A and Dejerine-Sottas syndrome.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Human, Monkey, Mouse, Rabbit (Lapine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PMP-22.
- Isotype: Rabbit Ig
- Gene: Q01453
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)