PP-1 Antibody
Product Details
- Cat. No.
- 250829
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Mouse
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Description
The protein phosphatase 1 (PP1) is essential for cell division and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PP-1 is involved in the regulation of ionic conductances and long-term synaptic plasticity. PP-1 plays an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. PP-1 holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The PP1 catalytic subunit can be PP1-alpha (PPP1CA), PP1-beta (PPP1CB) or PP1-gamma (PPP1CC), which is folded into its native form by inhibitor 2 and glycogen synthethase kinase 3, and then complexed to one or several targeting or regulatory subunits. This antibody recognizes PP1-alpha, PP1-beta and PP1-gamma.
Biological Information
- Clonality: Polyclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PP-1.
- Isotype: Mouse Ig
- Gene: P62136, P62140, P36873
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)