PP6C Antibody
Product Details
- Cat. No.
- 252096
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C A) is the catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PP6C A restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PP6C A downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. PP6C A is ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PPP6C.
- Isotype: Rabbit Ig
- Gene: O00743
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)