Product & ReviewsAntibodies
PRAME Rabbit pAb
Product Details
- Cat. No.
- A6456
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunofluorescence - PRAME antibody (A6456)
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Description
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
