Product & ReviewsAntibodies
Properdin (10C5) Antibody
Product Details
- Cat. No.
- 250304
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Properdin in plasma is a mixture of cyclic dimers, trimers and tetramers. The molecular weight of the glycosylated monomer is 53 kDa. Properdin is a regulator protein of the alternative complement pathway. It stabilizes the C3 convertase excerting its effect by binding to C3b in the C3bBb complex and thereby inhibiting cleavage of C3b by factor I and increasing the affinity for factor B. Serum concentration is approximately 25 µg/ml. This antibody is specific for human properdin.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Properdin isolated from human plasma (1)
- Clone: 10C5
- Isotype: Mouse IgG1/k
- Gene: P27918
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)