Product & ReviewsAntibodies
Proteinase 3 (3B4) Antibody
Product Details
- Cat. No.
- 252909
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
PRTN3 (Proteinase 3) is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human PRTN3 expressed in E. coli.
- Clone: 3B4
- Isotype: Mouse IgG2b
- Gene: P24158
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)