Product & ReviewsAntibodies
RABBIT ANTI ATG12 (INTERNAL REGION)
Product Details
- Cat. No.
- AHP1891
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Rabbit anti ATG12 (Internal Region) antibody recognizes human Autophagy-related protein 12 (ATG12). ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.There are at least two isoforms of ATG12.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Isotype: Polyclonal IgG
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.02% Sodium Azide
Applications
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)