RABBIT ANTI ATG5-ATG12 COMPLEX (C-TERMINAL)
Product Details
- Cat. No.
- AAM79
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Rabbit anti ATG5-ATG12 Complex antibody used for the evaluation of ATG5-ATG12 conjugate expression
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Description
Rabbit anti ATG5-ATG12 Complex antibody recognizes an epitope within the C-Terminal (CT) region of the Atg5-Atg12 complex, which plays a key role in the regulation of autophagy, and is emerging as an important factor in the innate immune response to viruses (Hwang et al. 2012).The Atg5-Atg12 complex interacts with retinoic acid–inducible gene 1 and the adaptor molecule IFN-beta promoter stimulator 1, through caspase recruitment domains, thereby acting as a negative regulator of the type I IFN production pathway, and as a contributor to RNA viral replication within the host cells (Takeshita et al 2008).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Isotype: Polyclonal IgG
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Western Blotting (WB)
