Product & ReviewsAntibodies

RABBIT ANTI BAX

Product Details

Cat. No.
AHP2421
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
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Bio-Rad

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Description

Rabbit anti BAX antibody recognizes the Bcl-2-associated X protein (BAX) also known as Bcl-2 like protein 4. BAX together with BAK (BCL-2 antagonist or killer), another member of the Bcl-2 family, plays a key role in the intrinsic apoptosis pathway by inducing mitochondrial outer membrane permeabilization (MOMP) (Giansanti and Scovassi 2008). This event is aided by BID (BH3-interacting domain death agonist), which activates the two proteins and thereby facilitates the formation of homo- or heterodimers. Often in the literature, MOMP is regarded as the point of no return upon which a cell is committed to undergo apoptosis (Chipuk et al. 2006).

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Isotype: Polyclonal IgG

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC DO NOT FREEZE
  • Buffer: Phosphate buffered saline, 0.1% Sodium Azide, 0.2% Gelatin

Applications

  • Western Blotting (WB)
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