RABBIT ANTI BAX
Product Details
- Cat. No.
- AHP2716
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Rabbit anti BAX antibody detects a band in cell lysates under reducing conditions
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Description
Rabbit anti BAX antibody recognizes the Bcl-2-associated X protein (BAX) also known as Bcl-2 like protein 4. BAX together with BAK (BCL-2 antagonist or killer), another member of the Bcl-2 family, plays a key role in the intrinsic apoptosis pathway by inducing mitochondrial outer membrane permeabilization (MOMP) (Giansanti and Scovassi 2008). This event is aided by BID (BH3-interacting domain death agonist), which activates the two proteins and thereby facilitates the formation of homo- or heterodimers. Often in the literature, MOMP is regarded as the point of no return upon which a cell is committed to undergo apoptosis (Chipuk et al. 2006).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: Polyclonal IgG
Handling
- Quantity: 50 µl
- Storage: -20ºC only
- Buffer: Phosphate buffered saline, 0.02% Sodium Azide, 50% Glycerol
Applications
- Western Blotting (WB)
