RABBIT ANTI BID
Product Details
- Cat. No.
- VPA00841
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot analysis of whole cell lysates probed with BID antibody
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Description
Rabbit anti Human BID antibody recognizes the BH3-interacting domain death agonist, also known as apoptic death agonist. BID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist Bcl-2. The encoded protein is a member of the Bcl-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined (provided by RefSeq, Jul 2008). Rabbit anti Human BID antibody detects a band of 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: Polyclonal IgG
Handling
- Quantity: 100 µl
- Storage: -20ºC only
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 50% Glycerol
Applications
- Western Blotting (WB)
