RABBIT ANTI CDKN2A

Rabbit anti Human CDKN2A antibody recognizes human cyclin-dependent kinase inhibitor 2A (CDKN2A), a 16 kDa protein belonging to the CDKN2 cyclin dependent kinase inhibitor family.CDKN2A acts as a negative regulator of cell proliferation by interacting strongly with CDK4 and CDK6, thus inhibiting their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein.CDKN2A is an important tumour suppressor and defects in its production results in tumour formation in a wide range of tissues, including cutaneous malignant melanoma and Li-Fraumeni syndrome.

• Clonality: Polyclonal
• Host: Rabbit
• Reactivity: Human, Human, Mouse, Rat
• Isotype: Polyclonal IgG

• Quantity: 0.1 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.02% Sodium Azide

• Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
• Western Blotting (WB)