RABBIT ANTI GLYCINE RECEPTOR ALPHA 1/2 (N-TERMINAL)
Product Details
- Cat. No.
- AHP929
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot of rat spinal cord snd hippocamapl lysates s
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Description
Rabbit anti glycine receptor recognises an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits.Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation.Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Isotype: Polyclonal IgG
Handling
- Quantity: 0.2 mg
- Storage: -20ºC after reconstitution
- Buffer: Ammonium bicarbonate
Applications
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Western Blotting (WB)
