Rabbit anti Human cytochrome p450 3A4 antibody used for the detection of P450 3A4 expressing cells
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Rabbit anti Human cytochrome p450 3A4 antibody recognizes human cytochrome p450 3A4 (CYP3A4). P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. Rabbit anti Human cytochrome p450 3A4 antibody is a neutralizing antibody, a specific and potent inhibitor of CYP3A4.
