Product & ReviewsAntibodies

RABBIT ANTI MOUSE TNF ALPHA

Product Details

Cat. No.
AAM19GA
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
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Bio-Rad

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Description

Rabbit anti Mouse TNF alpha antibody recognizes mouse Tumour Necrosis Factor alpha (TNF–alpha), a 17.3kDa multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts.TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-KappaB, the induction of apoptosis in various tumour cell lines and the stimulation of cell differentiation and proliferation under certain conditions. Studies have revealed a role for TNF-alpha in inflammation, septic shock, autoimmune disease and rheumatoid arthritis. This Rabbit anti Mouse TNF-alpha antibody can be used to neutralize the effects of mouse TNF-alpha.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Mouse
  • Isotype: Polyclonal IgG

Handling

  • Quantity: 0.1 mg
  • Storage: -20ºC only
  • Buffer: Phosphate buffered saline

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Western Blotting (WB)
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