Product & ReviewsAntibodies
RAD17 Antibody
Product Details
- Cat. No.
- 252171
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Cell cycle checkpoint protein RAD17 (RAD17) is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. RAD17 has a weak ATPase activity required for binding to chromatin. RAD17 participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEK1 activation. RAD17 is a sensor of DNA replication progression, and is involved in homologous recombination.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RAD17.
- Isotype: Rabbit Ig
- Gene: O75943
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)