Product & ReviewsAntibodies
RAN Antibody
Product Details
- Cat. No.
- 252027
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
GTP-binding nuclear protein Ran (RAN) is a GTP-binding protein involved in nucleocytoplasmic transport. RAN is required for the import of protein into the nucleus and also for RNA export. RAN is involved in chromatin condensation and control of cell cycle. The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. RAN enhances AR-mediated transactivation, which decreases as the poly-Gln length within AR increases.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chicken, Dog (Canine), Human, Mouse, Rat, Xenopus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human RAN.
- Isotype: Rabbit Ig
- Gene: P62826
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)