Product & ReviewsAntibodies
RAR-g mouse antibody (mAb) (Clone 4g-7A11), sample
Product Details
- Cat. No.
- 39974
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-g has two splice isoforms. RAR-g heterodimerizes with RXR and in the absence of ligand, the RAR/RXR dimer binds to hormone response elements complexed with co-repressor protein. Binding of agonist ligands to RAR results in dissociation of co-repressor and recruitment of coactivator protein which in turn promotes transcription of the downstream target gene into mRNA and eventually protein.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 4g-7A11
- Isotype: IgG1k
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Gel Super Shift Assay (GSS)
- Immunohistochemistry (IHC)
- Western Blotting (WB)