Product & ReviewsAntibodies

RAT ANTI DOG CD5:RPE

Product Details

Cat. No.
MCA1037PE
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Bio-Rad

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Description

Rat anti Dog CD5 antibody, clone YKIX322.3 recognizes canine CD5, a 67 kDa cell surface type 1 transmembrane glycoprotein also known as lymphocyte antigen T1, Ly-1 or Leu-1. CD5 is expressed on the surface of T-cells and thymocytes, CD5 is also expressed by NK cells at low levels (Huang et al. 2008). Rat anti dog CD5, cloneYKIX322.3 was clustered as canine CD5 in the First Canine Leucocyte Antigen Workshop (Cobbold et al. 1994).In a study of 73 cases of canine chronic lymphocytic leukemia (CLL) CD5 expression was absent on all cases of B-cell CLL as defined by CD21 expression and lack of CD3 or other T cell antigen expression (Vernau and Moore 1999). Rat anti dog CD5 serves as a useful marker for the discrimination of canine leukemias of differing origins (Deravi et al. 2017).

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Dog (Canine)
  • Isotype: IgG2a

Handling

  • Quantity: 100 TESTS/1ml
  • Storage: +4ºC DO NOT FREEZE
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Applications

  • Flow Cytometry (FC)
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