Product & ReviewsAntibodies

RAT ANTI MOUSE CD11b

Product Details

Cat. No.
MCA711
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Bio-Rad

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Description

Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.Rat anti Mouse CD11b antibody, clone 5C6 immunoprecipitates a heterodimer of ~165 and ~95 kDa. This clone also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Human, Mouse
  • Isotype: IgG2b

Handling

  • Quantity: 1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunoprecipitation (IP)
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