Product & ReviewsAntibodies

RAT ANTI MOUSE CD120a:RPE

Product Details

Cat. No.
MCA2078PE
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Bio-Rad

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Description

Rat anti Mouse CD120a antibody, clone HM104 recognizes an extracellular region of mouse CD120a, also known as TNF receptor type I (TNFR1). TNFR1 is an ubiquitously expressed transmembrane glycoprotein and member of the tumor necrosis factor receptor (TNFR) superfamily, which plays a key role in regulating the inflammatory response, acting as a receptor for tumor necrosis factor alpha (TNF-alpha) and lymphotoxin-alpha (TNF-beta). CD120a also plays a role in apoptosis, cytokine induction, cell differentiation, tumor necrosis and early stages of graft-versus-host disease, and its soluble form sTNFR1, acts as an inhibitor of TNF-alpha induced responses by acting as a decoy receptor.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Isotype: IgG2a

Handling

  • Quantity: 100 TESTS
  • Storage: +4ºC DO NOT FREEZE
  • Buffer: Phosphate buffered saline, 0.02% Sodium Azide, 0.5% BSA

Applications

  • Flow Cytometry (FC)
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