RAT ANTI MOUSE CD197
Product Details
- Cat. No.
- MCA2367GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat anti Mouse CD197 antibody, clone 4B12 recognizes murine C-C chemokine receptor type 7, also known as CD197, Epstein-Barr virus-induced G-protein coupled receptor 1, CCR7 or MIP-3 beta receptor. CD197 is a 354 amino acid ~43 kDa member of the G-protein coupled receptor family. In mice, CD197 is expressed on most naïve T cells, a subset of memory T cells, B cells, mature dendritic cells, NK cells, a subset of thymocytes and CD34+ macrophage progenitor cells.CD197 is a functional receptor for chemokines CCL21 and CCL19. The receptor plays an important role in regulating the trafficking and homing of lymphocytes and dendritic cells to secondary lymphoid organs.Rat anti Mouse CD197 antibody, clone 4B12 does not block the binding of the ligand to CD197.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunoprecipitation (IP)