Product & ReviewsAntibodies

RAT ANTI MOUSE CD283

Product Details

Cat. No.
MCA5891GA
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Bio-Rad

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Description

Rat anti Mouse CD283 antibody, clone 11F8 recognizes mouse TLR3, otherwise known as CD283 or Toll-like receptor 3. CD283 is a 905 amino acid ~105 kDa single pass type 1 transmembrane glycoprotein associated with endosomal membranes and member of the Toll-like receptor (TLR) family. CD283 functions as a receptor for double-stranded RNA (UniProt: Q99MB1).TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents. TLRs also initiate cell signaling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Isotype: IgG2a

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Immunofluorescence (IF)
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