Product & ReviewsAntibodies
RAT ANTI MOUSE CD44
Product Details
- Cat. No.
- MCA4703
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
Description
Rat anti Mouse CD44 antibody, clone IM7 recognizes CD44, also known as H-CAM, HUTCH and lymphocyte antigen 24 (Ly-24).CD44 is a cell surface receptor for hyaluronic acid, although it can also interact with other ligands such as collagens and matrix metalloproteinases. This protein plays a role in a variety of cellular functions, such as adhesion, lymphocyte activation and lymph node homing. It is also involved in cell migration and plays a role in tumor metastasis. CD44 has many distinct isoforms responsible for its functional diversity. Rat anti Mouse CD44 antibody, clone IM7 recognizes all isoforms of CD44 and has been reported to inhibit a delayed-type hypersensitivity response in vivo and to induce complement-mediated cytotoxicity.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Baboon, Bovine, Cat (Feline), Cynomolgus Monkey, Dog (Canine), Ferret, Horse (Equine), Human, Mouse, Mustelid, Pig (Swine), Rhesus Monkey
- Isotype: IgG2b
Handling
- Quantity: 0.25 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)